1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the procedure of several myeloma. Its synthesis or examine is vital for ensuring the purity and protection in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-one): A key compound from the synthesis of imatinib, a drug that targets specific varieties of most cancers, which includes Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers which include breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their research is essential for optimizing the generation system and ensuring significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to treat breast cancer, and 3-d]pyrimodin-5-yl)ethyl]benzoic acid these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the cure of breast most cancers. Numerous intermediates help in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis 2'-Difluoro-2'-deoxycytidine-3' of paclitaxel, a chemotherapy drug powerful in managing cancers such as ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and tiny cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved with the synthesis of adamantane derivatives, that have numerous purposes, which includes antiviral Attributes.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-4 to regulate blood sugar amounts.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of assorted gluconic acid derivatives, which happen to be Employed in food stuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication applied to control variety 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).